Anosmia is a complete loss of smell while parosmia is abnormal smell. Because the COVID virus and Long COVID is still relatively new, we are not completely clear yet on how or why the COVID virus causes the loss of smell or abnormal smell/taste. Unlike similar colds, this change or loss of smell doesn’t occur because of nasal congestion or stuffy nose. Recent findings suggest that this occurs because of a dysregulation of the autonomic nervous system (ANS), persistent damage in the nasal epithelium, vascular dysfunction, and neuroinflammation of the olfactory nerves from direct viral damage. Olfactory epithelium are full of ACE2 receptors making them prime targets for the covid virus.
Often, anosmia that occurred during the acute phase of the covid infection will turn into parosmia later on.
Stellate ganglion block has been the most successful so far for smell and taste restoration both for parosmia/dysgeusia and anosmia/ageusia.
Also, while there are no current studies published on this, I have personally found that EAT has helped some of my patients regain smell using several procedures of EAT. Other treatments that have worked have been:
None of these are effective for every single person suffering from smell and taste disturbances.
In general, smell training has not been effective in restoring smell and taste. There has been some limited success from stem cell injections into the olfactory cleft area, but the studies were not specific on the amount of recovery.
Hyposmia is a muted sense of smell. Everything smells normally just very muted. This form of smell abnormality is more resistant to treatment if it occurs from long covid.
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